Publication
714
Chem. Commun. , 48, 8772-8774, 2012
DOI: 10.1039/C2CC34511K
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Homogeneous electrochemical monitoring of exonuclease III activity and its application to nucleic acid testing by target recycling |
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Rebeca Miranda-Castro, Damien Marchal, Benoît Limoges and François Mavré
Laboratoire d’Electrochimie Moléculaire, UMR 7591 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 15 Rue Jean-Antoine de Baïf, F-75205 Paris Cedex 13, France
A simple and fast electrochemical nucleic acid assay based on a target recycling strategy and the release of a double-stranded DNA intercalating redox probe upon digestion of a specific duplex by exonuclease III is demonstrated. |
